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An ingenious electrochemical aptasensor for detection of CYFRA 21-1 based on dual-output toehold mediated strand displacement reaction.

Bioelectrochemistry, 2022
Herein, a "signal-on" electrochemical aptasensor based on dual-output toehold mediated strand displacement reaction (TMSDR) was developed to detect cytokeratin fragment antigen 21-1 (CYFRA 21-1).
Jinzhi Liu   +5 more
semanticscholar   +1 more source

Predictive role of CYFRA 21-1 for S-1 monotherapy in non-small cell lung cancer patients.

Respiratory Investigation, 2022
BACKGROUND S-1, an oral fluoropyrimidine derivative, is widely used for the treatment of several solid tumors. However, there are no predictive markers for its effectiveness. METHODS We retrospectively screened 108 patients with advanced non-small cell
Yusuke Kagawa   +14 more
semanticscholar   +1 more source

Copper doped terbium metal organic framework as emitter for sensitive electrochemiluminescence detection of CYFRA 21-1.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2021
Lanthanide metal organic frameworks (L-MOFs) are emerging as promising electrochemiluminescence (ECL) emitters for bioanalysis. This work proposed a copper doped terbium MOF as a luminescent tag for construction of a "signal-on" ECL immunosensing method.
Limin Zhou   +6 more
semanticscholar   +1 more source

A Co-Reactive Immunosensor Based on Ti3C2Tx MXene@TiO2-MoS2 Hybrids Promoting luminol@Au@Ni-Co NCs Electrochemiluminescence for CYFRA 21-1 Detection.

ACS Sensors
The construction of assays is capable of accurately detecting cytokeratin-19 (CYFRA 21-1), which is critical for the rapid diagnosis of nonsmall cell lung cancer.
Xiang Ren   +7 more
semanticscholar   +1 more source

Ultrasensitive label-free detection for lung cancer CYFRA 21-1 DNA based on ring-opening polymerization.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2021
Cytokeratin fragment antigen 21-1 (CYFRA 21-1) DNA is perceived as sensitive tumor marker for the diagnosis of non-small cell lung cancer and other tumor.
Xiaofei Li   +6 more
semanticscholar   +1 more source

Diagnostic value of serum squamous cell carcinoma antigen and cytokeratin fragment antigen 21-1 for sinonasal inverted papilloma: an exploratory study.

Rhinology
BACKGROUND Serum tumor markers have not yet been developed for the clinical diagnosis and treatment of sinonasal inverted papilloma (SNIP), one of the most significant sinonasal tumors.
Z. Zhang   +6 more
semanticscholar   +1 more source

Synergistic Assembly of 1DZnO and Anti-CYFRA 21-1: A Physicochemical Approach to Optical Biosensing

BME Frontiers
Objective: We conducted a comprehensive physicochemical analysis of one-dimensional ZnO nanowires (1DZnO), incorporating anti-CYFRA 21-1 immobilization to promote fast optical biomarker detection up to 10 ng ml−1.
R. A. Salinas   +7 more
semanticscholar   +1 more source

Confinement-enhanced electrochemiluminescence by Ru(dcbpy)32+-functionalized γ-CD-MOF@COF-LZU1 porous hybrid material as micro-reactor for CYFRA 21-1 detection.

Talanta: The International Journal of Pure and Applied Analytical Chemistry
The improvement of electrochemiluminescence (ECL) performance relies on the electron transfer efficiency between luminophore and coreactant. An ultrasensitive ECL micro-reactor with confinement-enhanced performance was prepared by using the covalent ...
Xiang Ren   +9 more
semanticscholar   +1 more source

Label-free electrochemical immunoassay for detecting CYFRA 21-1 using poly(ε-caprolactone)-b-poly(ethylene oxide) block copolymer

Microchemical journal (Print), 2021
As importance of early diagnosis, prognosis, and clinical monitoring in improving survival rate of lung cancer is increasing, the advance of effective diagnostic method for tumor marker is crucial.
Yawen Zhang   +5 more
semanticscholar   +1 more source

A self-powered photoanode-supported photoelectrochemical immunosensor for CYFRA 21-1 detection based on In2O3/In2S3/CdIn2S4 heterojunction.

Biosensors & bioelectronics, 2020
A self-powered photoanode-supported photoelectrochemical (PEC) immunosensor was designed based on In2O3/In2S3/CdIn2S4 as photoanode and PDA@CNTs as biocathode for the detection of CYFRA 21-1.
Tingting Wu   +9 more
semanticscholar   +1 more source

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