Results 161 to 170 of about 90,880 (281)

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann   +12 more
wiley   +1 more source

Splatshop: Efficiently Editing Large Gaussian Splat Models

open access: yesComputer Graphics Forum, EarlyView.
Abstract We present Splatshop, a highly optimized toolbox for interactive editing (selection, deletion, painting, transformation, …) of 3D Gaussian Splatting models. Utilizing a comprehensive collection of heuristic approaches, we carefully balance between exact and fast rendering to enable precise editing without sacrificing real‐time performance. Our
Markus Schütz   +5 more
wiley   +1 more source

Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement

open access: yesGeophysical Monograph Series, Page 27-82., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm   +2 more
wiley  

+1 more source

UBVH: Unified Bounding Volume and Scene Geometry Representation for Ray Tracing

open access: yesComputer Graphics Forum, EarlyView.
Abstract Bounding volume hierarchies (BVHs) are currently the most common data structure used to accelerate ray tracing. The existing BVH methods distinguish between the bounding volume representation associated with the interior BVH nodes and the scene geometry representation associated with leaf nodes.
M. Káčerik, J. Bittner
wiley   +1 more source

Assessment and Management of the Impact of Bovine Brucellosis on Dairy Herd Performance and Profitability. [PDF]

open access: yesVet Sci
Martínez-Guerrero O   +6 more
europepmc   +1 more source

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