Results 51 to 60 of about 32,723 (263)
Advanced Science, EarlyView.This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang +9 more
wiley +1 more source
Management Dynamics in the Knowledge Economy, 2015 IT&C instruments have been introduced in teaching and learning in order to facilitate the acquisition of competences and develop abilities for using new media and technologies.
Lavinia Cornelia BUTUM +2 more
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The Zooarchaeology of Israelite Religion: Methods and Practice
Religions, 2019 This essay aims to provide a methodological framework for the application of zooarchaeology to the study of Israelite religion for the purpose of providing an overview of this growing subfield for the non-specialist and for inviting further conversation ...
Jonathan S. Greer
doaj +1 more source
Advanced Science, EarlyView.Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan +7 more
wiley +1 more source
Women’s Voice and Religious Utterances in Ancient Greece
Religions, 2011 This paper tackles the issue of women and religion through a particular looking glass: religious utterances such as curses, supplication, and prayer, as reflected in some passages from ancient Greek epic and tragedy—pivotal literary genres in the ...
Manuela Giordano
doaj +1 more source
Advanced Science, EarlyView.Supramolecular hydrogels enable real‐time visualization of mechanical stress through supramolecular switching mechanotransduction. Adamantane‐modified cellulose functions as a responsive domain that undergoes an on–off transition between hydrated and dehydrated states via reversible β‐cyclodextrin–adamantane complexation and decomplexation.
Sooyeon Noh +7 more
wiley +1 more source
Why there is no biography of Stefan the first-crowned? [PDF]
Baština, 2019 Almost all the rulers of the Nemanjić Dynasty have their biographies, in more or less extensive forms, so do all the Serbian archbishops and the first three patriarchs.
Đekić Đorđe N.
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Advanced Science, EarlyView.Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang +7 more
wiley +1 more source
Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications
Angewandte Chemie, EarlyView.Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika +9 more
wiley +2 more sources
Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
Advanced Science, EarlyView.This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source