Results 51 to 60 of about 30,045 (266)

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

Dynamics of the Cult of Sheik Hussein of Bale, Ethiopia: Its Course and Curse of the Extremists, a Historical Perspective

open access: yesEthiopian Journal of the Social Sciences and Humanities, 2016
This article explores historical dynamics, values and emerging threats to the cult of Sheik Hussein of Bale. Oral, archival and secondary sources have been collected and crosschecked in the interpretation.
Kefyalew Tessema Semu
doaj   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

open access: yesAdvanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

open access: yesAdvanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon   +8 more
wiley   +1 more source

Pompous ladies and guarded children – Early Iron Age special burials at Dürrnberg ‘Eislfeld’ (Austria) [PDF]

open access: yesStudia Hercynia, 2020
The Dürrnberg ‘Eislfeld’- necropolis was intermittently excavated from 1963–2003. One of the largest and most important cemeteries of the northern alpine salt centre, the ‘Eislfeld’ is characterized by the size and abundancy of grave furnishings. Similar
Holger Wendling
doaj  

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

open access: yesAdvanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding   +12 more
wiley   +1 more source

Raphael’s Religious Paintings and Their Early Restorations: Devotional Attention or Aesthetic Appreciation?

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2013
This essay explores whether early restorers responded to the cult status of Raphael’s paintings, since Vasari records that several of his religious works carried spiritual power.
Cathleen Hoeniger
doaj   +1 more source

Nonlinear Ion‐Specific Control of Underwater Adhesion by Bottlebrush Polymer Interfaces

open access: yesAdvanced Science, EarlyView.
The efficiency of underwater adhesion is modulated by ion‐specific effects. Strongly hydrated Na+ remains separated from the mica surface by its hydration shell, preserving access to binding sites, whereas weakly hydrated K+ can partially dehydrate and occupy ditrigonal cavities.
Chang‐Sheng Wang   +10 more
wiley   +1 more source

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