Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase
Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal +7 more
wiley +1 more source
The many faces of the GID/CTLH E3 ligase complex. [PDF]
Alpi AF +3 more
europepmc +1 more source
Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley +1 more source
Reproductive fluids, commercial media, and organoids: bridging the gap in IVF culture systems. [PDF]
Hernández-Díaz N +3 more
europepmc +1 more source
Academics with Clay Feet? Anthropological Perspectives on Academic Freedom in Twenty-First Century African Universities. [PDF]
Nhemachena A, Mawere M.
europepmc +1 more source
The Bounded World: Void Architecture in Cult Dynamics and High-Control Groups
Part of the Void Framework research project (Moreright DAO).
openaire +2 more sources
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip +12 more
wiley +1 more source
Stakeholder-based assessment of historical urban landscapes as cultural heritage within the context of sustainable development: a case study of İznik (Nikaia). [PDF]
Kapuci U +3 more
europepmc +1 more source
Looking beyond interaction: exploring meaning making through the windows of an art gallery. [PDF]
Harris L.
europepmc +1 more source
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source

