Results 221 to 230 of about 120,908 (305)

The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age‐Dependent Structural Deficits in the Kidney

Aging Cell, Volume 25, Issue 5, May 2026.
During kidney aging, loss of the MICOS complex drives cristae disorganization, impairs oxidative capacity, and alters mitochondrial dynamics. MICOS disruption elevates mitochondrial ROS and disrupts calcium homeostasis, linking mitochondrial structural remodeling to metabolic dysfunction in aging kidney tissue.
Prasanna Katti, Praveena Prasad, Sepiso K. Masenga, Prasanna Venkhatesh, Zer Vue, Andrea G. Marshall, Benjamin Rodriguez, Han Le, Edgar Garza‐Lopez, Alexandria Murphy, Brenita Jenkins, Ashlesha Kadam, Jianqiang Shao, Amber Crabtree, Pamela Martin, Chantell Evans, Mark A. Phillips, David Hubert, Nelson Wandira, Okwute M. Ochayi, Dhanendra Tomar, Clintoria R. Williams, Jennifer Gaddy, Briar Tomeau, LaCara Bell, Taneisha Gillyard, Markis' Hamilton, Vineeta Sharma, Mohd Mabood Khan, Elma Zaganjor, Olujimi A. Ajijola, Estevão Scudese, Tyne W. Miller Fleming, André Kinder, Chandravanu Dash, Anita M. Quintana, Bret C. Mobley, Julia D. Berry, Pooja Jadiya, Dao‐Fu Dai, Annet Kirabo, Oleg Kovtun, Jenny C. Schafer, Sean Schaffer, Renata Oliveira Pereira, Debra D. Murray, Joyonna Gamble‐George, Melanie R. McReynolds, Antentor Hinton Jr   +48 more
wiley   +1 more source

On the Optimal Selection of Mel‐Frequency Cepstral Coefficients for Voice Deepfake Detection

Expert Systems, Volume 43, Issue 5, May 2026.
ABSTRACT The continuous evolution of techniques for generating manipulated audio, known as voice deepfakes, and the widespread availability of tools that produce convincing forgeries have created an urgent need for reliable detection methods. This work considers the dimensionality of Mel‐Frequency Cepstral Coefficients (MFCCs) as a core design variable
Sergio A. Falcón‐López, Llanos Tobarra, Antonio Robles‐Gómez, Rafael Pastor‐Vargas   +3 more
wiley   +1 more source

Clues for glues: from serendipity to nature's blueprints in degrader discovery. [PDF]

Essays Biochem
Kozicka Z.
europepmc   +1 more source

Deciphering the biosynthetic pathways of lichen acids

New Phytologist, Volume 250, Issue 3, Page 1784-1799, May 2026.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim, Tânia Keiko Shishido, Huong T. Pham, Kyo Bin Kang, Rundong Liu, Matti Wahlsten, Jérôme Collemare, Hyun Park, Soon‐Ok Oh, Hyung‐Ho Ha, Hangun Kim, Jae‐Seoun Hur   +11 more
wiley   +1 more source

A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation. [PDF]

Nat Commun
Langousis G, Gainza P, Hunkeler M, Kapsitidou D, Donckele EJ, Annunziato S, Wiedmer L, Jones KFM, DeMarco B, Quan C, Bunker RD, Lumb KJ, Fasching B, Castle JC, Townson SA, Bonenfant D.   +15 more
europepmc   +1 more source

Prenylcysteine Oxidase 1 Deficiency Protects the Cardiac Muscle Cell Line HL‐1 Against Ischaemic/Hypoxic Stress

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Ischaemic/hypoxic stress leads to heart remodeling and dysfunction. PCYOX1 promotes cardiomyocyte survival during injury, reducing the generation of reactive oxygen species. PCYOX1 deficiency regulates key proteins to preserve cardiomyocyte structure and function such as creatine kinase.
Cristina Banfi, Lisa Brocca, Alice Bascucci, Giulia Giusy Papaianni, Alice Mallia, Sonia Eligini   +5 more
wiley   +1 more source

South Tyrol (Italy) <i>Pastinaca sativa</i> L. subsp. <i>sativa</i> Essential Oil: GC-MS Composition, Antimicrobial, Anti-Biofilm, and Antioxidant Properties. [PDF]

Molecules
Di Girolamo D, Badalamenti N, Castagliuolo G, Ilardi V, Varcamonti M, Bruno M, Zanfardino A.   +6 more
europepmc   +1 more source

Contextualizing ancient texts with generative neural networks. [PDF]

Nature
Assael Y, Sommerschield T, Cooley A, Shillingford B, Pavlopoulos J, Suresh P, Herms B, Grayston J, Maynard B, Dietrich N, Wulgaert R, Prag J, Mullen A, Mohamed S.   +13 more
europepmc   +1 more source

(Re)defining urban villages and their potential in sustaining local authenticity: A case study of Da Lat, Viet Nam. [PDF]

PLoS One
Doan KA.
europepmc   +1 more source

The Sarapeion of Thessaloniki : An Architectural and Cultic Overview [PDF]

Aggelos Mefsout
openalex   +1 more source