Results 161 to 170 of about 1,214,655 (290)

Study on the driving mechanism of cultivated land change in the urban-rural fringe with Bayesian network modeling. [PDF]

Sci Rep
Wang J, Zhu Z, Chen M, Zhang Y.
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Population structure of wild and cultivated grapevines in Armenia. [PDF]

BMC Plant Biol
Nikoghosyan M, Hovhannisyan E, Zadirako N, Duan S, Asatryan A, Arakelyan A, Margaryan K, Baloyan A, Konecny T, Binder H.   +9 more
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Comparative metabolomic analysis in roots of natural and cultivated Astragalus membranaceus in Mongolia. [PDF]

Bot Stud
Tsednee M, Hsu CY, Sakamoto S, Mitsuda N, Tsolmon B, Chan MT, Yeh CM.   +6 more
europepmc   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

Advanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever   +7 more
wiley   +1 more source

High‐Performance Ternary Organic Solar Cells via Isomeric Engineering of Nonfullerene Guest Acceptors

Advanced Science, EarlyView.
Two isomeric nonfullerene acceptors, BTP‐γ‐Br and BTP‐δ‐Br, were designed to investigate their effects on the optoelectronic properties and photovoltaic performance of ternary blends. Incorporating BTP‐γ‐Br into the D18:N3 binary system can enhance film crystallinity and suppress charge recombination, achieving a high PCE of 19.2% and a certified JSC ...
Zhenzhong Pan, Renjie Xu, Yuanyuan Jiang, Guangliu Ran, Kerui Liu, Wenkai Zhang, Meisu Zhou, Liheng Feng, Xiaozhang Zhu   +8 more
wiley   +1 more source

Comparison of the effects of natural, cultivated, and synthetic musk on preventing acute cerebral ischemia/reperfusion injury in rats. [PDF]

J Tradit Chin Med
Tianyu L, Weiying L, Huayang T, Fu P, Cheng P, Xiaoqi P.   +5 more
europepmc   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Metabolomics and Microbiomics Reveal the Cultivation-Dependent Divergence in Ginsenoside Biosynthesis and Rhizosphere Ecology of <i>Panax ginseng</i>. [PDF]

Metabolites
Liu S, Wu D, Ma W, Wang T, Yan B, Ge Y, Xiong F, Wang H, Kang C.   +8 more
europepmc   +1 more source