Results 161 to 170 of about 383,400 (219)

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen   +6 more
wiley   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

open access: yesAdvanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang   +9 more
wiley   +1 more source

Synergized Tri‐Phase Anode via Purposive Ba2+ Doping at the La3+ Site in LaFe0.7Ni0.3O3‐δ for Improved SOFC Performance

open access: yesAdvanced Science, EarlyView.
Purposive doping of low electronegative Ba2+ (0.89) at La3+ (1.1) site in LaFe0.7Ni0.3O3‐δ induces the formation of a tri‐phase composite, which shortens Fe─O bond and lowers activation energy, thereby significantly improves electrical conductivity and catalytic activity, and finally offers a record‐high peak power density in La0.5Ba0.5Fe0.7Ni0.3O3‐δ ...
Qian Yang   +11 more
wiley   +1 more source

Correction: Cultivation viability of <i>Allium tuberosum</i> L. in the Western Ghats: insights into crop dynamics, yield and quality. [PDF]

open access: yesFront Plant Sci
Gavhane AD   +9 more
europepmc   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li   +14 more
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy