Results 81 to 90 of about 8,256,561 (256)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Vygotsky L.S.

Культурно-историческая психология, 2021
Vygotsky L.S.
doaj   +1 more source

The Psychological Content of Relationship between Sense and Meaning in Cultural-Historical Approach

Культурно-историческая психология, 2018
The paper considers L.S. Vygotsky’s cultural-historical theory and its interpretation in modern psychology. It shows that psychological content of many concepts introduced by L.S. Vygotsky differs greatly from that of the ones used in theory and practice
Kravtsova E.E., , Kravtsov G.G.,
doaj   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Lecture Four. Structure and Functions of Cultural Operations in Children

Культурно-историческая психология, 2021
Vygotsky L.S.
doaj   +1 more source

Principles and practices of methodology and methods in cross-cultural psychology

, 2022
Principles of methodology in (cross-)cultural psychology are discussed and how these work out in practice. We propose that the frequently mentioned contrasts between context-specificity and universality of psychological functioning, and between ...
Poortinga, Ype H., Fontaine, JohnnyPP098010016462290000-0002-5684-0178F67A0928-F0ED-11E1-A9DE-61C894A0A6B4   +1 more
core  

Positive psychology and ideas of cultural-historical school of L.S. Vygotsky

Культурно-историческая психология, 2017
In the article was carried out a comparative analysis between two distinctive psychology schools: the cultural-historical psychology of L.V. Vygotsky and the positive psychological school.
Vasilev V.K.,, Stamatov R.I.,
doaj   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Developing the Ideas of the Scientific School of L.S. Vygotsky: Scientific Publications of the Journal “Cultural-Historical Psychology” (2005—2016)

Культурно-историческая психология, 2016
The article presents the analysis of the development of the ideas of L.S. Vygotsky’s school using the example of the publications in the international scientific journal “Cultural-Historical Psychology” (for the period 2005 through 2016). Over the period
Shvedovskaya A.A.,
doaj   +1 more source

The Children’s Playground in the Context of Cultural-Historical Psychology

, 2016
The article describes the possible application of the principles of cultural-historical approach and activity theory to the inspection of toys and play environments.
Smirnova E.O.,, Kotliar I.A.,, Sokolova M.V.,, Sheina E.G.,   +3 more
core   +1 more source