Results 201 to 210 of about 948,490 (246)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Translation, cultural adaptation, and validation of the Geriatric Depression Scale - Short Form into Bengali among elderly people in Bangladesh. [PDF]

PLOS Glob Public Health
Arif MH, Acharjee P, Sajib MWH, Haque MM, Rimti FH, Chowdhury MAK.   +5 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Culture matters? Family norms, living arrangements, and loneliness in China. [PDF]

SSM Popul Health
Cai S, Li W, Wang J.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

When motivation is not enough: the moderating role of social support in cross-cultural adaptability among Chinese students learning Arabic. [PDF]

Front Psychol
Huang Y, Chen J.
europepmc   +1 more source

Culturally sensitive stress management strategies for parents of preterm infants in the NICU: a systematic review of qualitative evidence protocol. [PDF]

BMJ Open
Chen YC, Chang MY, Wu TY.
europepmc   +1 more source

Cultural barriers to stunting prevention: a case study of the Baduy indigenous tribe in Indonesia. [PDF]

Front Sociol
Adi YA, Pujihartati SH, Humsona R, Wirasisya DG.   +3 more
europepmc   +1 more source

Global minds and local contexts: grand challenges and emerging opportunities in cultural psychology. [PDF]

Front Psychol
Jia F.
europepmc   +1 more source

Translation and cultural adaptation to the Brazilian context of the Organizational Readiness to Change Assessment scale. [PDF]

Epidemiol Serv Saude
Benedetti TRB, Alves TF, Santos N, Rech CR, Claumann GS, Silva FB.   +5 more
europepmc   +1 more source