Results 71 to 80 of about 948,490 (246)

The Evolution of Wellness Models: Implications for Women’s Health and Well-Being

open access: yesInternational Journal of Women's Health
Heba Yaagoub AlNujaidi, Saja A Al-Rayes, Arwa Alumran College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Heba Yaagoub AlNujaidi, Email Hnujaidi@iau.edu.saAbstract: The concept of wellness goes beyond the
AlNujaidi HY, Al-Rayes SA, Alumran A
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

UNA INVESTIGACIÓN INTRA-CULTURAL DE LIDERAZGO EN MÉXICO: IGUALDAD EN LAS PYMES DE HIDALGO, COLIMA Y TAMAULIPAS

open access: yesRevista Facultad de Ciencias Económicas, 2008
La presente investigación expone las prácticas de liderazgo en 301 Pequeñas y Medianas Empresas (PyMEs). 121 del estado de Hidalgo, 87 de Colima y 93 de Tamaulipas, del país, México.
VÍCTOR HUGO ROBLES FRANCIA
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Tuberculosis risk factors in Lephalale local municipality of Limpopo province, South Africa

open access: yesSouth African Family Practice, 2017
Lephalale local municipality is the leading sub-district in Limpopo province with 9.8% of deaths caused by tuberculosis. This study aimed to describe the risk factors for TB in Lephalale local municipality.
Takalani G Tshitangano   +3 more
doaj   +1 more source

Cultural Communication

open access: yesPeriferica, 2018
Strategic communication is a key marketing tool in the management of cultural organisations. Both internally and externally, the aim is to maximise the efficiency of investments in instruments of communication, in order to successfully achieve coherent and integrated communication which is capable of adapting to the changes and challenges continually ...
openaire   +6 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

JOSÉ MARTÍ’S UNIVERSAL ANALYSIS OF EDUCATION FROM A HUMANIST AND CULTURAL PERSPECTIVE / LA UNIVERSALIDAD DEL ANÁLISIS DE JOSÉ MARTÍ SOBRE LA EDUCACIÓN DESDE SU PERSPECTIVA HUMANISTA Y CULTURAL

open access: yesDidasc@lia: didáctica y educación, 2010
José Martí did not study teaching profession, he neither devoted his life for developing this profession, but he delivered lessons in different Latin-Americans countries and he did it with an undoubtable excellence according to some testimonies and ...
Recaredo Benito Rodríguez Bosch
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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