Results 141 to 150 of about 4,591,608 (378)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The cross-cultural adaptation of Chinese international students: an empirical study on sequential-mediated effects

Frontiers in Psychology
Using convenience sampling and snowball sampling methods, data from 432 Chinese international students in 10 countries, including the United Kingdom, South Korea, and the United States, were collected to construct a multivariate sequential-mediated mixed
Chenglong Miao, Chenglong Miao, Shuai Zhang, Shuai Zhang   +3 more
doaj   +1 more source

Cross-cultural adaptation and validation of the fremantle neck awareness questionnaire into brazilian portuguese in individuals with chronic neck pain [PDF]

, 2023
Gabriel Henrique Santin Apahaza
openalex  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

BRIDGES OF HEALTH: HOW EDUCATION, FAMILY, AND CULTURE SHAPE MIGRANT INTEGRATION IN THE CZECH REPUBLIC FROM A PUBLIC HEALTH PERSPECTIVE

Клінічна та профілактична медицина
Introduction. Migration is a multifaceted process that goes beyond physical relocation, involving the integration of individuals into new social, cultural, and economic environments. In the Czech Republic, where the number of migrants is steadily rising,
Renata Švestková, Lesia Shuranova, Jitka Vacková, Radka Prokešová, Klaudie Němečková   +4 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Life experiences and cultural adaptation among migrant workers in Malaysia

Comparative Migration Studies
This study examines the state of migrants’ cultural adaptation in Malaysia, and how such an adaptation can help build our understanding of migrants’ life and employment experiences in the country.
Azlizan Mat Enh, Andika Wahab, Arina Anis Azlan, Kartini Aboo Talib, Andi Muhammad Tri Sakti, Fazal Mohamed Mohamed Sultan   +5 more
doaj   +1 more source

Brief report: cultural adaptations for the PEERS program for Latine families

Frontiers in Education
BackgroundThe UCLA PEERS program has been studied using predominantly White and affluent populations. As autistic teens and their parents are represented across cultures, it is vitally important that interventions are tailored to their needs–whether that
Ann Marie Martin, Ann Marie Martin, Jan Blacher, Elina Veytsman, Elizabeth Baker, Jill Fodstad, Katherine Meltzoff   +6 more
doaj   +1 more source

Author's Reply for Letter to the Editor on “American Orthopedic Foot and Ankle Society Hallux Metatarsophalangeal-Interphalangeal Joint Scale: A Cross-Cultural Adaptation and Validation Study in the Persian Language” [PDF]

, 2022
Hamideh Mahdaviazad, Amir Reza Vosoughi
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source