Results 51 to 60 of about 538,969 (317)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A new methodological approach to nonverbal behavior analysis in cultural perspective [PDF]
The measurement of human behavior is a complex task, both for psychologists and human sciences researchers and with respect to technology, since advanced and sophisticated instruments may have to be implemented to manage the plurality of variables involved.
Agliati, Alessia +2 more
openaire +2 more sources
Measuring the economic contribution of cultural industries [PDF]
This 2012 update of a 2009 study provides an overview of current methods for measuring the contribution of cultural industries in today’s economy.Cultural industries are becoming important components of today’s economy, propelling innovation and ...
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Whose place? Sustaining cultural conversations [PDF]
: The notion of place is integral to any understanding of cultural sustainability. Present and future places are the product of the political negotiations of past places.
Shanene Ditton
core
The Tensions between Ukuthwasa and Labour Laws in South Africa: A Human Rights-Based Approach [PDF]
This paper appraises the tensions between the cultural practice of ukuthwasa and fundamental human rights in South Africa. This is particularly within the context of modern labour laws and workplace practices. A doctrinal research methodology is employed
Stewart Lee Kugara +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Main Approaches to Historical and Cultural Analysis of the Films [PDF]
The article deals with the XX century — a century of active development, the visual technology diffusion, that have shaped a new way of thinking. Nowadays we can note the special role of «visuality» in everyday life, which has become almost ubiquitous: movies, advertising, photo signboard, television.
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

