Results 111 to 120 of about 638,387 (355)

Culture, art, technology, and perception: A creative generation model for museum cultural and creative product design

open access: yesInternational Journal of Innovative Research and Scientific Studies
This study is dedicated to an in-depth exploration of the key elements and internal mechanisms of the creative generation of museum cultural and creative products (MCCPs). Given the fragmented state of previous studies and the lack of a unified framework, this study aims to gain a deeper understanding of the creative process of MCCP design.
Daocai Han, Siow-Kian Tan, Booi-Chen Tan
openaire   +1 more source

The creative country: policy, practice and place in New Zealand's creative economy 1999-2008 [PDF]

open access: yes, 2010
The ‘creative industries’ have emerged as one of the dominant elements of the ‘knowledge economy’ in the 21st century. As promoted by academic researchers such as Richard Florida, the ‘creative class’ has been associated with high profile industries such
Smith, Jason McLaren
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Beyond Souvenirs: Consumption Values of Cultural and Creative Products From Museums

open access: yesSAGE Open
Museums play a vital role in tourism, and as venues for shopping, are conventionally associated with souvenirs. Cultural and creative products from museums have gained popularity in China in recent years, but visitors’ purchase of these products remains ...
Haipeng Jin, Anyang Hu
doaj   +1 more source

Meningkatkan Citra UKM Melalui Perancangan Ulang Identitas Visual

open access: yesHumaniora, 2014
The shift of economic trend into creative economy spurs Indonesia as a creative nation supported with cultural diversity, creative human resources and rich of natural resources to actively participate and contribute to the global economy.
Lintang Widyokusumo
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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