Results 121 to 130 of about 637,329 (305)
Place-making strategies of culturepreneurs. The case of Frankfurt/M., Germany [PDF]
The paper describes the emergence of a new hybrid cultural and entrepreneurial agent in the context of the local cultural industries of Frankfurt on Main (Germany).
Lange, Bastian
core
Cities: The cultural dimension [PDF]
, 2014 In the last 50 years culture has undergone a dramatic shift in meaning and practice. In the post-War period a narrow social elite set dominant cultural values.
Pratt, A.C.
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Customer Engagement Around Cultural and Creative Products: The Role of Social Identity. [PDF]
Front Psychol, 2022 Zhang Z, Li W.
europepmc +1 more source
How often do you wash your hair? design as disordering: everyday routines, human object theories, probes and sustainablity [PDF]
, 2007 New objects can create disorder in our lives particularly when we try to appropriate and make sense of newly developed products that do not fit our routines.
Cooper, T., Fisher, T., Hielscher, S.
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Application of "Dongdong tui" Mask Cultural Genes in Leather Cultural and Creative Products
Pige Kexue Yu GongchengThe Dong ethnic group's "Dongdong tui" Nuo mask, as the material carrier of Dong traditional art and religious ceremonies, not only inherits a unique artistic style, but also contains a rich cultural essence.
Xin XIAO, Jinfeng WANG
doaj +1 more source
From creativity to innovation [PDF]
Talent is the bedrock of a creative society. Augmenting talent involves mobilizing culture and tradition, building institutions to increase the stock of human capital, enhance its quality, and instill values favoring achievements and initiative.
Yusuf, Shahid
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source