Results 151 to 160 of about 637,329 (305)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Research on University Cultural and Creative Product Design [PDF]
Advances in Social Science, Education and Humanities Research, 2022 openaire +1 more source
Creative tourism special issue: foreword [PDF]
, 2019 This Tourism and Management Studies Special Issue on Creative Tourism is born under the scope of a very original project: the CREATOUR - Creative Tourism Destination Development in Small Cities and Rural Areas.
Cabeça, Sónia Moreira +3 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Creative methodologies for understanding a creative industry [PDF]
, 2011 The chapter presents a conceptual framework for the identification and analysis of value creating and value capture systems within creative industry contexts based on theoretical and empirical studies.
Fuller, Ted +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Consuming identity : the case of Scotland [PDF]
, 2001 The paper examines national identity in Scotland. The research explores how consumers perceive the symbols used to represent Scotland, how these symbols relate to their perceptions of contemporary Scottish identity and their responses to the use of these
Coombes, Emma +3 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Towards a European Spatial Policy for Culture [PDF]
The European space finds itself in a moment of profound change. On one hand it is adapting to the challenges that are inherent to the global, post-industrial economy.
Antonio Russo, Jan van der Borg
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GoGlobal: How can contemporary design collaboration and e-commerce models grow the creative industries in developing countries? [PDF]
, 2009 Using previous case studies by the authors and a current live project, this paper considers whether the creative industries in a developing country (Ghana, Africa) can be nurtured through design collaboration and an e-commerce model to contribute ...
Barker, Tom, Hall, Ashley
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