Results 71 to 80 of about 638,387 (355)

Zenélés a „víg gettóban”. A cseh underground 1968 és 1989 között [PDF]

open access: yes, 2015
ArticleText in HungarianThis study presents an empirical case study of the Czech Underground community, focusing on actors’ entrance into, and experience within, the Underground from the late 1960s to 1980s.
Hagen, Trever
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Branding Brazilian slums through 'freeware' cultural production: the case of Rio de Janeiro [PDF]

open access: yes, 2012
This paper reflects on a "cultural industry model" with important potential for local development, which is the network of independent cultural producers of Brazilian slums. The landscape of favelas is unique: plagued by poverty and crime, they have come
Russo, Antonio
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Investigating the Impact of Museum Cultural and Creative Products on Consumers’ Cultural Interest: A Case Study of Dunhuang

open access: yesIEEE Access
This research aims to explore the impact of museum cultural and creative products on consumers’ cultural interest. Based on previous literature, this research proposed a research model to explore the crucial factors influencing consumers’ ...
Yichen Ye, Xiaofan Yu
doaj   +1 more source

Perceptions of creativity amongst university design tutors [PDF]

open access: yes, 2001
The possibility to suppress the nonperturbative effects choosing the vary high multiplicity final state is discussed.
Jones, Paul   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Investigation and research on cultural and creative design products based on Hui culture

open access: yesHighlights in Art and Design, 2022
As a representative of China's classical architectural culture, Huipai culture has always been a pioneer highlight in the development of China's cultural industry. However, in recent years, as local cultures continue to recognize the importance of the development of cultural industries, a large number of cultural and creative products based on the ...
Fosong Kong, Cheng Wang
openaire   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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