Results 71 to 80 of about 86,519 (254)

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

open access: yesAdvanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab   +16 more
wiley   +1 more source

Shapes, scents and sounds:quantifying the full multi-sensory basis of conceptual knowledge [PDF]

open access: yes, 2013
Contemporary neuroscience theories assume that concepts are formed through experience in multiple sensory-motor modalities. Quantifying the contribution of each modality to different object categories is critical to understanding the structure of the ...
Hoffman, Paul, Lambon Ralph, Matthew A
core   +2 more sources

Transparent Transfer‐Free Ultrasmall Multilayer Graphene Microelectrodes Enable High Quality Recordings in Brain Slices

open access: yesAdvanced Science, EarlyView.
A transfer‐free fabrication method enables multilayer graphene microelectrodes as small as 10 µm, eliminating reliability issues of manual graphene transfer. These electrodes record neural activity in brain slices with exceptional signal‐to‐noise ratios (up to 25–40 dB) while maintaining optical transparency for multimodal applications.
Nerea de Alvarez de Eulate   +7 more
wiley   +1 more source

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

open access: yesAdvanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai   +8 more
wiley   +1 more source

Experiencing digital fashion archives through a decolonial lens

open access: yesEuropean Journal of Cultural Management and Policy
Fashion archives, as repositories of cultural memory, often reflect and perpetuate colonial legacies through their curation, classification, and accessibility practices.
Victoria Rodriguez Schon   +1 more
doaj   +1 more source

Social Situatedness: Vygotsky and Beyond [PDF]

open access: yes, 2002
The concept of ‘social situatedness’, i.e. the idea that the development of individual intelligence requires a social (and cultural) embedding, has recently received much attention in cognitive science and artificial intelligence research.
Lindblom, Jessica, Ziemke, Tom
core  

The Memory Palace:Telling the Story of the Interior [PDF]

open access: yes, 2012
This book chapter originated as an invited keynote paper at the Interior Educators 'Interior Futures 'conference at Northumbria University in 2011. The paper was blind peer revwied for publication.
Hollis, Edward
core   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Being there and being then: Ideal presence and historical tourism [PDF]

open access: yes, 2011
Should history be affecting? Should we engage with it emotionally? These concerns were central to eighteenth and nineteenth century historiography and remain relevant to historians, especially public historians.
Weston, Rowland
core   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

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