Results 31 to 40 of about 347,213 (305)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transtornos alimentares: o papel dos aspectos culturais no mundo contemporâneo Transtornos alimentarios: el papel de los aspectos culturales en el mundo contemporáneo Eating disorders: the role of cultural aspects in the contemporary world

open access: yesPsicologia em Estudo, 2010
Os transtornos alimentares são patologias caracterizadas primordialmente pelo medo mórbido de engordar. Vários são os fatores envolvidos tanto na etiologia quanto na manutenção e na gravidade dessas doenças, principalmente fatores individuais, familiares
Leticia Langlois Oliveira   +1 more
doaj   +1 more source

Psychosocial and cultural aspects of pseudocyesis

open access: yesIndian Journal of Psychiatry, 2008
Though considered rare in the developed countries, pseudocyesis is fairly common in gynecological practices in Africa. Using a case report and an overview of the literature, this paper posits that the elucidation of the psychosocial and cultural contexts within which a given patient lives can provide a basis for the empathic understanding of the ...
Ibekwe, Perpetus C., Achor, Justin U.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Cross-cultural aspects of international business [PDF]

open access: yes, 2023
Об’єктом дослідження є багатогранні виміри крос-культурних аспектів у міжнародному бізнесі. Предметом дослідження є вивчення кроскультурності міркування та стратегії, які використовують міжнародні компанії у своїй діловій практиці.
Hrytsai, Yu.V.
core  

Hoje preciso refletir um pouco: ser social e tempo histórico na obra de Chico Buarque de Hollanda 1971/1978 Today it is necessary to reflect a little bit: social being and historical time on Chico Buarque de Hollanda's songs. 1971/1978

open access: yesHistória, 2003
Este artigo analisa a relação entre o ser social e o tempo histórico em cinco canções compostas por Chico Buarque de Hollanda durante os anos 70, em plena vigência do regime militar no Brasil.
Marcos Napolitano
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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