Results 81 to 90 of about 7,438,965 (258)
Afiche 8M - Casa cultural tejiendo sororidades
, 2020 Esta postal se realizó para convocar a la conmemoración del 8 de Marzo Día Internacional por los derechos de la mujer, en el año 2020 en las sedes de la Casa Cultural ...
Casa cultural tejiendo sororidades
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Ethnomathematics: the cultural aspects of mathematics [PDF]
Revista Latinoamericana de Etnomatemática, 2011 Ethnomathematics studies the cultural aspects of mathematics. It presents mathematical concepts of the school curriculum in a way in which these concepts are related to the students¿ cultural and daily experiences, thereby enhancing their abilities to ...
Milton Rosa, Daniel Clark Orey
doaj +1 more source
Purdue University Black Cultural Center, Cultural Celebrations, Treasured Resources
, 2022 Purdue University Black Cultural Center Cultural Celebrations Treasured Resources Jahari Dance Troupe Black voices of Inspiration New Directional Players Haraka Writers Performing Arts Ensembles Art Collection Library Research ...
Purdue University. Black Cultural Center
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Developmental aspects in cultural neuroscience
Developmental Review, 2018 Research in cultural neuroscience and development examines the processes and mechanisms underlying the interaction of cultural systems with environmental and biological systems with a life course approach. Culture interacts with environmental and biological factors to shape the mind, brain and behavior across stages of development.
openaire +3 more sources
Commodification of Cultural Heritage [PDF]
, 2016 Outputs from IPinCH\u27s "Commodification of Cultural Heritage" Research ...
Intellectual Property Issues in Cultural Heritage
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source