Results 41 to 50 of about 2,196,045 (307)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Cross-Cultural Reading Comprehension Assessment in Malay and English as it Relates to the Dagostino-Carifio Model of Reading Comprehension

open access: yesCurrent Issues in Education, 2013
The review of existing literature suggests that few researchers have adopted cross-language comparisons to explore how cultural background affects the assessment of reading comprehension of students.
Lorraine Dagostino   +3 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Liberal Democracy: Culture Free? The Habermas-Ratzinger Debate and its Implications for Europe

open access: yesAustralian and New Zealand Journal of European Studies, 2011
The increasing number of residents and citizens with non-Western cultural backgrounds in the European Union (EU) has prompted the question of whether EU Member States (and other Western democracies) can accommodate the newcomers and maintain their free ...
Pablo C. Jiménez Lobeira
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Cultura, competencia comunicativa y superación de los especialistas de museos Culture, communicative competence and professional development of museum specialists [PDF]

open access: yesTransformación, 2017
The new socio-economic context of the 21st century set new challenges to museums, among them to become interactive institutions in the community, meeting the expectations of the public and giving support to school education.
Niola Fuentes Felicó
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

End of Life Care: The Importance of Culture and Ethnicity [PDF]

open access: yes, 2010
Despite Australia's cultural diversity, there is little doubt that ethnic minority groups continue to have less access to health care systems, let alone culturally appropriate care, including palliative and end of life care.
Jane Phillips
core  

Social and Cultural Capital and Learners’ Cognitive Ability: Issues and Prospects for Educational Relevance, Access and Equity Towards Digital Communication in Indonesia [PDF]

open access: yes, 2020
In the educational context, the necessity of recognizing the structure of relations among social and educational institutions by examining how individuals’ different social and cultural experiences affect the educational learning outcomes towards global ...
Maunah, Binti
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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