Results 41 to 50 of about 2,217,595 (287)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The effects of cultural capital on academic achievement: A secondary analysis of a PISA study [PDF]

Nastava i Vaspitanje, 2017
This paper presents the results of a secondary analysis of empirical data obtained as part of a Programme for International Student Assessment (PISA) study conducted in 2009.
Štrangarić Snežana Z., Rodić-Lukić Vesna N., Marić Mia R.   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Escala de Capital Cultural

Política e Gestão Educacional
Este estudo visa validar a Escala de Capital Cultural nas Interações Familiares por meio de evidências de validade, centrando-se na estrutura interna do instrumento desenvolvido pelos autores.
Alexandre Chaves Nunes, Josemberg Moura de Andrade   +1 more
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Creating Cultural Capital

Artivate, 2016
This ambitious volume eloquently frames cultural entrepreneurship as a “critical paradigm” for artistic creators, scholars, students, and policymakers to ethically engage the communities where they work.
Paul Bonin-Rodriguez
doaj  

Qué nos enseña el capital cultural para pensar el capital erótico

Educação & Sociedade, 2015
En el presente artículo recupero ciertos análisis sobre el capital cultural. Con ellos me interrogo acerca de su utilidad para analizar el capital erótico. El trabajo se centra, fundamentalmente, en dos problemas.
José Luis Moreno Pestaña
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Can Adolescents Acquire Cultural Capital Through Social Capital Access and Exposure? Experimental Evidence of the Impact of Ties to College-Educated Adults

AERA Open
Scholars question whether cultural capital reproduces existing inequalities or leads to upward mobility. While families provide opportunities to increase cultural capital, schools value and reward cultural capital.
S. Michael Gaddis, Joseph Murphy
doaj   +1 more source

Journalists, Numeracy and Cultural Capital

Numeracy, 2016
Journalists are tasked with holding power to account; often, that means evaluating and interpreting numbers. But anecdotally, journalists are ill at ease with figures.
Steven Harrison
doaj   +1 more source