Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas+24 more
wiley +1 more source
Military Service Roles and ALS Among Veterans: A Matched Case–Control Study
ABSTRACT While military service is an established risk factor for amyotrophic lateral sclerosis (ALS), it remains unclear whether this association is linked to combat. We conducted a matched case–control study comparing 191 ALS patients who were veterans of the Israeli Defense Forces (IDF) with known military service type and 1910 matched controls. The
Asaf Honig+4 more
wiley +1 more source
Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions. [PDF]
Edward M, Muhigi S, Mundua J, Ally A.
europepmc +1 more source
ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su+19 more
wiley +1 more source
Healthcare workers' attitudes regarding the assessment of dementia in the elderly. [PDF]
Živanović S+4 more
europepmc +1 more source
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte+13 more
wiley +1 more source
The role of formal social networks in mitigating age-related mental stress among older Nigerians living in poverty: Insights from social capital theory. [PDF]
Folorunsho S, Sanmori M, Suleiman M.
europepmc +1 more source
Research on the supply-demand balance evaluation and driving mechanism of community public service facilities. [PDF]
Chen J+5 more
europepmc +1 more source
The effect of an educational program on knowledge about sexual abuse prevention among child laborers: a quasi-experimental study. [PDF]
Begjani J+4 more
europepmc +1 more source
Translation and Cross-Cultural Adaptation of the Instrument for the Diagnosis of the Complexity of Palliative Care Needs. [PDF]
Canzani F+11 more
europepmc +1 more source