Results 41 to 50 of about 140,997 (296)

Analysis of fire evacuation scenarios in children's cultural centers

open access: yesJournal of Safety Science and Resilience
Fires that occur in assembly buildings cause great loss of life and property. Children's cultural centers included in assembly buildings should also be evaluated within this context.
Muammer Yaman, Cüneyt Kurtay
doaj   +1 more source

Analysis of educational bases of cultural-educational centers of mosques [PDF]

open access: yesمسائل کاربردی تعلیم و تربیت اسلامی, 2023
Objective: The present study aims to identify and analyze the educational foundations of mosque-centered schools, seeking to answer the following question: “Which foundations do these schools adhere to and what goals and principles do they follow ...
Zahra SalehiMotaahed   +2 more
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Cultural centres and their role the Cultural Centre Novi Pazar and the Cultural Centre of Serbia (Paris) [PDF]

open access: yesGlasnik Etnografskog Instituta SANU, 2017
This paper open a discussion on the functioning of cultural centers, as (potentially) influential institutions at local and international level. Authors wish is, by analyzing the program of the Cultural Centre Novi Pazar and the Cultural Centre ...
Aksić Nina, Pantović Branislav
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ROLE OF THE POLITICAL AND CULTURAL educational CENTRES IN THE PEASANT MASSES UNIFICATION ON THE TERRITORY OF KURSK PROVINCE IN 1920-1927s: PECULiARITIES AND FIRST RESULTS

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2018
We study one of the most specific forms of work to build political and cultural educational centres in the peasant masses unification. That work was not directly connected with administrative and command methods.
A. Y. Ryadnykh
doaj   +1 more source

Tourist valorization of the old city center of Novi Sad according to the Hillary Du Cros model [PDF]

open access: yesGlasnik Srpskog Geografskog Društva, 2006
Cities are ambiental, but also complex cultural tourist motifs. Different elements are combined in them, such as: attractiveness of architecture modern accomplishments, centers of cultural, artistic and sports life etc. Old city centers play an important
Romelić Jovan   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

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