Results 41 to 50 of about 4,594,987 (303)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Ankara Araştırmaları DergisiCulture exhibits a complex relationship that exists within architecture and urban environments, particularly in how space is manifested through diverse settings.
Feyza Topçuoğlu
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Culture Unbound: Journal of Current Cultural ResearchThis study explores the socio-spatial dynamics surrounding the creation and perception of Sara kulturhus, a flagship cultural centre in Skellefteå, Sweden. While initially being framed within a discourse of urban attractivity, the project later became
Evelina Liliequist, Anna Sofia Lundgren
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A framework for cultural heritage management and research: the Cancellara case study
Journal of Maps, 2018 This paper deals with the approach used to create the digital cultural heritage map (hereafter, c.h.) of the mountain village of Cancellara and its territory, located in Basilicata, Southern Italy.
Marilisa Biscione +2 more
doaj +1 more source
Innovative Practices and Mechanism Building of Delivering Cultural Center's High-Quality Service to the Grassroots Level [PDF]
Nongye tushu qingbao xuebao[Purpose/Significance] The direct delivery of high-quality services by cultural centers to the grassroots level serves as a crucial pathway for fulfilling their industry mission and promoting high-quality development.
HUANG Jianliang, WANG Yufu
doaj +1 more source
, 2020 This thesis investigates the principles underlying traditional Japanese architecture and landscape design and proposes the ways by which these principles can be applied to design in a modern context. To give a clear picture and understanding of these principles, the thesis starts with a brief review of the historical and cultural background of Japan ...
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source