Results 91 to 100 of about 469,863 (306)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Cold War seen from the 21st century. Interpretive novelties

open access: yesPasado y Memoria, 2019
In the existing literature on the Cold War published since 2000, the different authors reviewed in this essay study this conflict from an epistemological perspective and novel historiography.
José Antonio Lorenzo Cuesta
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Foreword

open access: yesActa Academiae Artium Vilnensis
The conference Art Beyond the Politics: Africa and the ‘Other’ Europe during the Cold War, planned by the Vilnius Academy of Arts in 2022, was intended to explore the often-overlooked cultural exchanges between Central-Eastern Europe and Africa during ...
Karolina Jakaitė, Karina Simonson
doaj  

Patrick Iber, Neither Peace nor Freedom. The Cultural Cold War in Latin America

open access: yesPrismas, 2018
Patrick Iber, Neither Peace nor Freedom. The Cultural Cold War in Latin America, Cambridge (ma) y Londres, Harvard University Press, 2015, 327 ...
Ximena Espeche
doaj  

The Global Dimensions of Conflict in Sri Lanka [PDF]

open access: yes
This paper seeks to identify and chart the global dimensions of the political conflict and civil war in Sri Lanka. The global dimensions are visualised in terms of the ways in which the dynamic of the conflict has been embedded within two parallel and ...
Rajesh Venugopal
core  

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

The Binding of Abraham: Inverting the Akedah in Fail-Safe and WarGames [PDF]

open access: yes, 2015
This article draws upon Søren Kierkegaard's Fear and Trembling and Jacques Derrida'sThe Gift of Death to trace how two exemplars of atomic bomb cinema reinterpret the Binding of Isaac (Akedah).
Dukes, Hunter B
core   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

The Heritage of the Cold War in Contemporary Curricula and Educational Reforms

open access: yesCenter for Educational Policy Studies Journal, 2019
Using a theoretical-critical and historical approach, this paper analyses the implications of the Cold War in national curricula and educational reforms of the second half of the 20th century with emphasis on the 21st century.
Tomislav Topolovčan   +1 more
doaj   +1 more source

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