Results 41 to 50 of about 469,863 (306)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Discourse Beyond Borders: Periodicals, Dissidents, and European Cultural Spaces

open access: yesJournal of European Periodical Studies, 2018
Émigré periodicals in Cold War Europe have long been considered isolated islands of Central and East European communities with limited relevance. In the second half of the Cold War, some of these periodicals functioned as crucial intersections of ...
doaj   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Exploring the Path of ‘Domestic Appropriation’ in the English Translation of Cold Mountain Poetry from the Perspective of Translation Studies [PDF]

open access: yesSHS Web of Conferences
Cold Mountain poems originally came from the Tang Dynasty poet-monk Hanshan, whose creative style is unique. Cold Mountain poems were accidentally introduced to Europe and the United States in the post-World War II period and caused a great uproar.
Zhang Aohan
doaj   +1 more source

Book review: understanding the imaginary war: culture, thought and nuclear conflict, 1945-90 edited by Matthew Grant and Benjamin Ziemann [PDF]

open access: yes, 2017
In Understanding the Imaginary War: Culture, Thought and Nuclear Conflict, 1945-90, editors Matthew Grant and Benjamin Ziemann offer a collection focusing on how the unknowable and inconceivable – nuclear war – was necessarily imagined during the Cold ...
Curtis, April
core  

Culture, Power and Identity the Case of Ang Hien Hoo, Malang [PDF]

open access: yes, 2017
This paper discusses the intricate relations between culture and identity in a web of larger power structures of politics and the market by looking at the ways in which the Indonesian Chinese attach themselves to a local performing arts tradition.
Budianta, M. (Melani)
core   +4 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

A ‘cultural Cold War’?

open access: yesIndonesia and the Malay World, 2019
This article examines the development of the Institute of People’s Culture (Lembaga Kebudayaan Rakyat, Lekra) in West Java in the 1950s and 1960s.
openaire   +3 more sources

British Anti-Soviet Media Operations in Poland (1947–1948)

open access: yesFacta Simonidis
The escalating Cold War necessitated the intensification of Western efforts against the dissemination of the Soviet ideology in the USSR’s satellite countries.
Ewelina Gdaniec
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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