Results 51 to 60 of about 469,863 (306)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Cultural Cold War Goes “Vulgar”: Radio Serial Melodrama in Post–Korean War South Korea, 1956–1960

open access: yesInternational Journal of Communication, 2017
This study explores the birth of the popular radio serial drama under the Cold War doctrine of national broadcasting in 1950s South Korea. By examining texts, critiques, production practices, and writers, I interrogate how the anti-Communism propaganda ...
Bohyeong Kim
doaj   +2 more sources

Ambivalent Occidentalism in Mochtar Lubis’s Cold War Literature Maut dan Cinta

open access: yesJournal of Language and Literature
This article revisits Maut dan Cinta (1977), a seminal Cold War-era novel by Indonesian author Mochtar Lubis, to examine how the text engages with cultural imperialism in postcolonial Indonesia through its complex portrayal of the Occident.
Muhammad Taufiqurrohman   +2 more
doaj   +1 more source

The Flagship Institution of Cold War Turcology

open access: yesEuropean Journal of Turkish Studies, 2017
The study of the cultural Cold War, the untold story of how the USA and the USSR employed and often exploited the academia and the arts for war purposes, is now a particularly fruitful line of inquiry, but it has scarcely reached the field of Turkish ...
İlker Aytürk
doaj   +1 more source

The Perils of Intimacy: Harry Hopkins as Franklin D. Roosevelt's National Security Adviser [PDF]

open access: yes, 2009
The University Archives has determined that this item is of continuing value to OSU's history.Frank Costigliola is Professor of History at the University of Connecticut specializing in 20th century U.S. history and U.S. foreign relations.
Costigliola, Frank
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Remembering Poland: The Ethics of Cultural Histories [PDF]

open access: yes, 2002
Art Spiegelman\u27s Maus, Cynthia Ozick\u27s The Shawl, and Eva Hoffman\u27s Lost in Translation and Exit into History are recent American texts that draw upon cultural histories of Poland to launch their narratives.
Gorski, William
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Darlene J. Sadlier. Americans All. Good Neighbor Cultural Diplomacy in World War II.

open access: yesAnuario Colombiano de Historia Social y de la Cultura, 2014
This publication adds to a rapidly growing volume of scholarship on U.S. cultural diplomacy. Most of this scholarship focuses on the Cold War and on Europe. This volume, in turn, is concerned with a lesser-known episode that came to fruition during World
Gisela Cramer
doaj   +1 more source

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