Results 131 to 140 of about 465,315 (305)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Construction of Hong-dae cultural district : cultural place, cultural policy and cultural politics
, 2007 Cho M. Construction of Hong-dae cultural district : cultural place, cultural policy and cultural politics. Bielefeld (Germany): Bielefeld University; 2007.This dissertation examines how the process of creating the "Hong-dae cultural district" in Seoul ...
Cho, Mihye
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Background: Pain neuroscience education (PNE) can support understanding of low back pain and facilitate engagement with active care. Most PNE materials have been developed in English, and there is little culturally adapted content for Urdu-speaking ...
Cameron, Lainie +2 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Nowadays, it is more realistic to view the development of a new technology as a result of a complex social system of interactions and decisions. Understanding the public's range of views on biotechnology is important for decision makers, in order to be ...
Tsioumanis, Asterios +3 more
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Changing imperatives in third sector media and cultural production: a study of news production, documentary film-making and arts and cultural programming [PDF]
, 2012 Research on third sector media and cultural organisations has tended to focus on socio-political imperatives in organisational and production processes.
Mutibwa, Daniel Henry
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Towards a sound management of digital culture. Metadata schemes and application profiles for digital repositories [PDF]
, 2010 If we give a look to the present panorama of digital research – particularly if applied to cultural heritage collections - we have to admit that there is still more attention to the quality of data than to the necessary series of management activities ...
Feliciati, Pierluigi
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Cosmopolitan expertise : music, media and cultural identities in Italy [PDF]
My thesis explores the extent to which people's nationality informs their engagement with popular culture and strategies of social distinction (Bourdieu 1984). I address this question by studying the emergence of popular music criticism as a new cultural
Varriale, Simone
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