Results 101 to 110 of about 2,723,676 (306)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Russian Specialists’ Perception of Negotiations with Chinese Partners: Expectations, Strategies and Challenges

RUDN Journal of Psychology and Pedagogics
In the context of global challenges and changing geopolitical situations around the world, Russian organizations are increasingly facing the necessity of active cooperation with countries in the Far East, especially China. The purpose of this exploratory
Ekaterina D. Vasilyeva, Albina A. Gallyamova, Elizaveta Sh. Komyaginskaya, Nadezhda M. Lebedeva   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

How culture influences perspective taking: Differences in correction, not integration

Frontiers in Human Neuroscience, 2013
Individuals from East Asian (Chinese) backgrounds have been shown to exhibit greater sensitivity to a speaker's perspective than Western (US) participants when resolving referentially ambiguous expressions. We show that this cultural difference does
Shali eWu, Dale J Barr, Timothy Matthew Gann, Boaz eKeysar   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

THE IMPACT OF MANAGERIAL MULTICULTURAL COMPETENCES ON COMPANY’S COMPETITIVE ADVANTAGE IN GLOBAL ECONOMY [PDF]

Innovative Issues and Approaches in Social Sciences, 2014
In this article, we will present an empirical account on management of intercultural differences. The focus will be on managerial dilemma how to achieve the company’s competitiveness with adaptation to market forces as well as to the cultural environment
Rosana Grušovnik, Dejan Jelovac
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

You are What you Eat (and Drink): Identifying Cultural Boundaries by Analyzing Food & Drink Habits in Foursquare

, 2014
Food and drink are two of the most basic needs of human beings. However, as society evolved, food and drink became also a strong cultural aspect, being able to describe strong differences among people.
Almeida, Jussara, de Melo, Pedro O S Vaz, Loureiro, Antonio, Musolesi, Mirco, Silva, Thiago H   +4 more
core   +1 more source

COMPARATIVE ANALYSIS ON EASTERN AND CENTRAL EUROPEAN STUDENTS’ INTERCULTURAL SENSITIVITY. RESEARCH CONDUCTED IN ROMANIA, HUNGARY AND SLOVENIA [PDF]

Journal of Languages for Specific Purposes, 2016
The following study is meant to be an extension of and completion to a former research paper entitled “The Role of Foreign Language Teachers in Developing Students’ Intercultural Communication Skills” concluding that students of the University of Oradea,
Hamburg Andrea
doaj