Results 171 to 180 of about 2,723,676 (306)

Background check: cross-cultural differences in the spatial context of comic scenes. [PDF]

Multimodal Commun, 2023
Atilla F, Klomberg B, Cardoso B, Cohn N.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Cross-Cultural Differences in Public Discourse on COVID-19 Vaccination in the United States and South Korea: Cross-Sectional Analysis Using Natural Language Processing. [PDF]

JMIR Form Res
Youm S, Jang SH, Kwak H, Choi J, Yi YJ.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Commentary: Running the Risk

Journal of Trial and Error
Samantha Copeland, Stuart Firestein
doaj   +1 more source

Dynamic emotion recognition and learning motivation prediction in Chinese second language acquisition under cultural differences: a study based on ED-CM-MP model. [PDF]

Front Psychol
Hao J.
europepmc   +1 more source

Evidence for cultural differences in affect during mother-infant interactions. [PDF]

Sci Rep, 2023
Abu Salih M, Abargil M, Badarneh S, Klein Selle N, Irani M, Atzil S.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The Special Problem of Cultural Differences in Effects of Corporal Punishment [PDF]

, 2010
Lansford, Jennifer E.
core   +1 more source

Cultural Differences in Visual Attention Emerge in Infancy. [PDF]

Infancy
Heise MJ, Meristo M, Ueno M, Itakura S, Carlson SM.   +4 more
europepmc   +1 more source