Results 91 to 100 of about 1,207,433 (312)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Jurnal Studi Pemerintahan, 2016 Culture appears in all contexts of human life, included in the government's communication policy. The aim of this study is to verify the influence of the cultural dimension toward the communication policy of relocating street vendors by the Government of
LA MANI +3 more
doaj
國家間圖書版權貿易的經濟和文化因素分析 An Analysis of the Economic and Cultural Determinants of Copyright Trade among Some Asia Countries [PDF]
Jiàoyù zīliào yǔ túshūguǎn xué, 2005 本文通過分析中國大陸與5個儒家文化圈國家或地區在1998－2003年間的圖書版權貿易情況，探討經濟因素和文化因素在國家間圖書版權貿易中的相對重要性。本文發現，至少就中國大陸與亞洲儒家文化圈國家或地區間的圖書版權貿易而言，文化上的接近性或差異性對于版權貿易具有顯著影響，而對應國家的經濟發展水平則對圖書版權貿易并沒有顯著影響。This paper aims to explore the relative importance of economic and cultural factors in the ...
Jianbin Jin, Kete Wu
doaj
Integrating Culture in EFL: High Stakes and Thorny Issues
Altralang Journal, 2019 The starting point of the present paper is the strong conviction that the cultural dimension should be encompassed in EFL education. Indeed, cultural competence is a key factor in enhancing the learning of English and the comprehension of the bolts and ...
Habib YAHIAOUI
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Driving Factors for Sustainable Livestock Development in Indonesia: Study on Beef Cattle Commodities [PDF]
BIO Web of ConferencesDriving factors for the development of smallholder beef cattle farming include consumption needs and market availability, government policies and institutional, social and cultural support from the community, availability of animal feed sources ...
Amam Amam +3 more
doaj +1 more source
Cultural proximity and trade [PDF]
Cultural proximity increases bilateral trade flows through a trade-cost and a bilateral-affinity (preferences) channel. Conventional measures of cultural proximity, such as common language, common religion, etc., do not allow to separately quantify those
Felbermayr, Gabriel, Toubal, Farid
core
The Social Wellbeing of New York City's Neighborhoods: The Contribution of Culture and the Arts [PDF]
, 2017 This report presents the conceptual framework, data and methodology, and findings of a two-year study of culture and social wellbeing in New York City by SIAP with Reinvestment Fund.
Mark J. Stern, Susan C. Seifert
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
, 2013 Geert Hofstede’s seminal 1980 book, Culture’s Consequences: International Differences in Work-Related Values, along with its 2001 reissue and expansion and related journal articles, is without question the most influential work on culture in the field of international management.
openaire +1 more source