Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The different dimensions of livelihood impacts of Payments for Environmentals Services (PES) schemes: A systematic review [PDF]
Through a systematic review of peer-reviewed and grey literature, this paper analyzes evidence of the livelihood impacts of Payments for Environmental Services (PES). Forty-six studies assessed PES livelihood impacts.
Bax, Vincent +5 more
core +7 more sources
L’EMPREINTE CULTURELLE ET SA DYNAMIQUE DANS LE MILIEU PROFESSIONNEL. COMMUNICATION ET ADAPTATION INTERCULTURELLES DANS LES ENTREPRISES ITALO-ROUMAINES [PDF]
The present paper presents a few aspects reflecting the difficulties that Italian businessmen face when adapting to the Romanian social and cultural environment or when leading Romanian working groups and their reaction towards working with Italian ...
CATARIG ANDRA-TEODORA
doaj
Social representations of HIV/AIDS in five Central European and Eastern European countries: A multidimensional analysis [PDF]
Cognitive processing models of risky sexual behaviour have proliferated in the two decades since the first reporting of HIV/AIDS, but far less attention has been paid to individual and group representations of the epidemic and the relationship between ...
Alexandra Kozlova +29 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Designing for Diversity: How Culture Shapes Nano-learning in China and Europe
Cultural differences are an important determining factor in the way learners engage with digital education platforms designed in a way that requires a lot of contextual knowledge, for example, in Nano-learning.
Wanting He
doaj +1 more source
Cross Cultural Dimension of Cooperation
[China and South Asian countries have centuries-old civilisations, having strong influences. The legacy of civilisations and cultures determines the way of thinking and the tendency of policy-making.
Guo Suiyan
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
SURVEY OF TÂRNAVE VITICULTURAL LANDSCAPE
The aim of the article is to explain the Romanian context for inventories and analysis regarding landscape diversity, management and aesthetics. The main surveyed drivers of change are: (1) natural and cultural dimensions - geology, soils, climate ...
Adela Hoble +4 more
doaj +1 more source

