Results 71 to 80 of about 1,202,282 (291)

Humane Orientation as a New Cultural Dimension of the GLOBE Project: A Validation Study of the GLOBE Scale and Out-Group Humane Orientation in 25 Countries [PDF]

, 2012
We validate, extend, and empirically and theoretically criticize the cultural dimension of humane orientation of the project GLOBE (Global Leadership and Organizational Behavior Effectiveness Research Program).
Al Najjar, Musaed, Arciszewski, Thomas, Besevegis, Elias, Bishop, George, Bonnes, Mirilia, Clegg, Chris, Drozda-Senkowska, Ewa, Frese, Michael, Gaborit, Mauricio, Garzon, Dayra, Hansen, Tia, Heintze, Anna-Maria, Heszen, Irena, Juhász, Marta, Keating, Mary, Mangundjaya, Wustari, Mansor, Norma, Mitchelson, Jackie, Ortiz, Alejandra, Pandey, Janak, Pavakanun, Ubolwanna, Pavlopoulos, Vassilis, Peiró, Jose Maria, Potocnik, Kristina, Restrepo, Maria Helena, Schloesser, Oliver, Semmer, Norbert, Tupinamba, Antonio, Ventura, Elizabeth, Whoolery, Matthew, Zhang, Kan   +30 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

THE APPLICABILITY OF WIDELY EMPLOYED FRAMEWORKS IN CROSS-CULTURAL MANAGEMENT RESEARCH [PDF]

This article aims to analyze and assess the applicability of widely employed frameworks in cross-cultural management research. First, some criteria are conceptualized and then, eight cultural frameworks are examined and their relevance with respect to ...
Daniel Sauers, Hamid Yeganeh, Zhan Su
core  

Persuasive argumentation as a cultural practice [PDF]

, 2014
In this article author traces relation between argumentation and cultural practice. The first part focuses on definition of argumentation in informal logic tradition.
GAŁKOWSKI, Paweł
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

An Analysis of Diversity Management Through Cultural Dimensions

Theory, Methodology, Practice, 2010
Dealing with social pressure for equal treatment and opportunities has been one of the most important business issues in modern times. Countries are dealing with this issue in different ways, with different approaches and levels of maturity according to
Ana Sperancin
doaj  

Cartography of corruption in Colombia: an approach to the social, cultural and economic dimensions

Cogent Social Sciences
The study examines how corruption affects various dimensions in Colombia, specifically social, cultural and economic dynamics. It underscores the importance of analyzing the interrelations between corruption and democracy, ethics, human behavior, tourism,
Ibis Danilo Yanguas-Botero, Alexander Zúñiga-Collazos, Omar de Jesús Montilla-Galvis   +2 more
doaj   +1 more source

The Normative and Cultural Dimension of Work: Technological Unemployment as a Cultural Threat to a Meaningful Life. [PDF]

J Bus Ethics, 2023
Mejia S.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source