Results 131 to 140 of about 5,569,454 (345)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

[Review of] Arjun Appadurai, Modernity at Large, Cultural Dimensions of Globalization [PDF]

open access: yes, 1996
Modernity at Large is a collection of essays (most of which are reprinted from other sources, e.g., Public Culture) that link the themes of modernity and globalization to contemporary everyday social practice, and to group individual identity ...
Schau, Hope J.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Assimilation and Integration of Immigrants in Europe [PDF]

open access: yes
This paper documents assimilation of immigrants in European destinations along cultural, civic, and economic dimensions, distinguishing by immigrants' generation, duration of stay, and origin.
Aleksynska, Mariya, Algan, Yann
core  

Research on joint ventures in China: progress and prognosis [PDF]

open access: yes, 1996
Previous published studies on international joint ventures (JVs) in China are reviewed and assessed by summarising important research patterns. A model of management of international JVs in China is developed which emphasises the central theme of cross ...
Fan, Y
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Kültürün Reklamlar Üzerindeki Etkileri Perspektifinden Renault “Hayat Kadar Beklenmedik” Örneğine Göstergebilimsel Bir Bakış

open access: yesErciyes İletişim Dergisi
Kültür bir toplumun asırlık birikimiyle oluşmaktadır. Kültürel farklılıklar bazen bir törende, bazen bir kelimede, bazen bir yemekte bile gözlemlenebilmektedir.
Semih Kopuz, Metin Işık, Ebru Yılmaz
doaj   +1 more source

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