Results 131 to 140 of about 6,890,869 (329)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Leaders Role Within Cultural Industries [PDF]
In the increasingly turbulent and competitive environment business, the dilemmas experienced by managers in cultural industries are characteristic to this type of industries where knowledge and creativity are key to sustaining competitive advantage ...
Cristina MANOLACHE, Radu CAMENITA
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Caring Culture: Art, Architecture and the Politics of Public Health [PDF]
, 2011 Caring Culture: Art, Architecture and the Politics of Public Health examines changing political uses of the concept of care in neoliberal democracies and asks how artists, architects and designers both contribute to and attempt to critique its social ...
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Islam in China: Uyghurs in Crisis [PDF]
, 2020 Islam has been in China for hundreds of years and has been the religion to ten people groups in China, including the Uyghur people group. The Uyghurs have been under China’s domain since the mid-1700s and since then have stood out among the fifty-five ...
Baez, Isabella
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Droit & Anthropologie / Law & Anthropology, 2017 What does it mean for courts and other legal institutions to be culturally sensitive? What are the institutional implications and consequences of such an aspiration? To what extent is legal discourse capable of accommodating multiple cultural narratives without losing its claim to normative specificity?
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Multilingual search for cultural heritage archives via combining multiple translation resources [PDF]
, 2007 The linguistic features of material in Cultural Heritage (CH) archives may be in various languages requiring a facility for effective multilingual search.
Debole, Franca +4 more
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