Results 61 to 70 of about 597,963 (303)

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

The Ecological Dimension of Modern European Culture [PDF]

Современная Европа
In the article modern European culture is analysed in an ecological dimension through the model of cultural ecology/ecology of culture. The paradigm of cultural ecology is considered as a way to study the changing relations between culture and the ...
Elena V. Vodopianova
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Research communication [PDF]

, 2014
In this paper we review briefly histories and ideologies underlying multiculturalism in Nordic countries, highlighting tensions between integrationist and inclusive approaches.
Bayliss, Linda, Bayliss, Phil, Dillon, Patrick   +2 more
core  

Evolution in Archaeology [PDF]

, 2008
This review begins with a brief outline of the key concepts of Darwinian archaeology. Its history is then summarized, beginning with its emergence as a significant theoretical focus within the discipline in the early 1980s; its main present-day currents ...
Shennan, SJ
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Buddhist Approaches to Cultural Ecology by Means of Virtue Ethics

Journal of International Buddhist Studies, 2023
Humans are social beings that have a long history of development since the Paleolithic (the Old Stone Age) to the contemporary day and the IT world. Humans try to survive by creating cultures to correspond to the environment from generation to generation.
Natpiya Saradum
doaj  

REPRESENTATION OF CULTURE ECOLOGY IN WISRAN HADI’S PERSIDEN, GENERASI KETUJUH

Litera, 2019
Culture and humans are interdependent and fused by ecological processes and natural energy cycles. The author as the creator of the work cannot be separated from the cultural environment from which it originates.
Sugiarti Sugiarti, Candra Rahma Wijaya Putra   +1 more
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source