Results 131 to 140 of about 6,193,539 (305)
Allelic Variation at the Rht8 Locus in a 19th Century Wheat Collection
The Scientific World Journal, 2012 Wheat breeding during the 20th century has put large efforts into reducing straw length and increasing harvest index. In the 1920s an allele of Rht8 with dwarfing effects, found in the Japanese cultivar “Akakomugi,” was bred into European cultivars and ...
Linnéa Asplund +2 more
doaj +1 more source
FROM CULTURAL REVOLUTION TO CULTURAL EVOLUTION
Revista Científica Arbitrada de la Fundación MenteClara, 2018 En este artículo consideramos el concepto de la Revolución Cultural desde una perspectiva no convencional y enfatizamos que, en lo que respecta al concepto básico, la Revolución Cultural tiene especial relevancia para la sociedad moderna y puede concebirse como un esfuerzo colectivo para asegurar la elevación de la mente humana y las modalidades ...
openaire +4 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Experiments in Cultural Language Evolution
Human natural languages use quantifiers as ways to designate the number of objects of a set. They include numerals, such as ``three'', or circumscriptions, such as ``a few''. The latter are not only underdetermined but also context dependent.
Steels, Luc.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Cultural Formation of Preferences and Assimilation of Cultural Groups [PDF]
Based on the cultural formation of continuous preferences framework of Pichler (IMW Working Paper No. 431, 2010), this paper analyzes the evolution of preferences and behavior in a two cultural groups setting.
Michael M. Pichler
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East Asian Gene flow bridged by northern coastal populations over past 6000 years
Nature CommunicationsCoastal areas of northern East Asia in the ShanDong region, which show complex cultural transitions in the last 10,000 years, have helped to facilitate population interactions between more inland regions of mainland East Asia and islands such as those in
Juncen Liu +26 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Índices de impacto cultural: antecedentes, metodología y resultados
, 2014 El resultado que se registra en el presente documento es un hallazgo metodológico para la definición de una batería de indicadores de efecto e impacto cultural y para la construcción de índices de impacto cultural.
Banco de la República (Bogotá). Subgerencia Cultural
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source