Results 81 to 90 of about 6,748,108 (328)
Scientific ReportsFire plays a central role in human evolution and site formation, yet its impact on the preservation of microscopic use-wear remains poorly understood.
Alice Rodriguez +3 more
doaj +1 more source
Human Communication Systems Evolve by Cultural Selection [PDF]
, 2014 Human communication systems, such as language, evolve culturally; their components undergo reproduction and variation. However, a role for selection in cultural evolutionary dynamics is less clear.
Barr, Dale +3 more
core +1 more source
A systems approach to cultural evolution
Palgrave Communications, 2019 A widely accepted view in the cultural evolutionary literature is that culture forms a dynamic system of elements (or ‘traits’) linked together by a variety of relationships.
Andrew Buskell +2 more
semanticscholar +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The dynamics of norm change in the cultural evolution of language [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Social conventions, such as shaking hands or dressing formally, allow us to coordinate smoothly and, once established, appear to be natural. But what happens when a new convention replaces an old one?
R. Amato +3 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The evolutionary dynamics of how languages signal who does what to whom
Scientific ReportsLanguages vary in how they signal “who does what to whom”. Three main strategies to indicate the participant roles of “who” and “whom” are case, verbal indexing, and rigid word order.
Olena Shcherbakova +5 more
doaj +1 more source
Gender Differences in the Interest in Mathematics Schoolwork Across 50 Countries
Frontiers in Psychology, 2020 Although much research has found girls to be less interested in mathematics than boys are, there are many countries in which the opposite holds. I hypothesize that variation in gender differences in interest are driven by a complex process in which ...
Kimmo Eriksson, Kimmo Eriksson
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source