Results 51 to 60 of about 84,807 (263)

YMCC and YSN: An Opportunity for Scientific and Cultural Exchange. [PDF]

open access: yesJ Med Chem, 2023
Ferrins L   +7 more
europepmc   +2 more sources

Pre-service Teachers' Cognition of Subject Teaching Knowledge: Dilemmas, Reasons and Strategies

open access: yesJiaoshi jiaoyu xuebao
Pre-service teachers' cognition of subject teaching knowledge consists of teachers' cognition of subject knowledge and teaching practice. Based on 27 reflection reports from 9 pre-service teachers, this study applies the qualitative research method to ...
GUO Xuejun, LIN Lin, LI Na
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Culture as Bridge between France and Romania in the Early Period of the Communist Regime

open access: yesLinguaculture
The establishment of the communist regime in Romania led to the country’s diplomatic isolation in the first years after 1948. Western states were considered enemy states from an ideological point of view, therefore diplomatic, economic and cultural ...
Cristina Preutu
doaj   +3 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An Analysis of Blooket Performance in Intermediate Mandarin Reading Course

open access: yesMandarinable
This study aims to analyze the effectiveness of using a Blooket as a gamified learning tool in an intermediate-level Mandarin reading class. Using a descriptive quantitative approach based on User Experience (UX), additional data were collected through ...
Tiffany Qorie   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Capitais ibéricas da resistência antiditatorial e anticolonialista: redes e cumplicidades no mundo da edição nos anos 1960-70

open access: yesCatalonia, 2020
This text deals with the exchange resulting from the intervention of publishers and booksellers who, supported by networks woven from their organizations based in the Iberian capitals, marked the politico-cultural and civic resistance within the walls ...
Daniel Jorge Seixas de Melo
doaj   +1 more source

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