Results 41 to 50 of about 25,794 (210)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
ETHNO-CULTURAL IDENTIFICATION IN THE CONTEXT OF MODERN SOCIETY
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The aim of the article is the study of cultural peculiarities of ethnical identity on the example of the Sakha (Yakut) people. The author also makes research on the processes of identification in present ethno-cultural and social conditions.
Popova Galina Semyonovna
doaj +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
GLOBALIZATION AND CULTURAL IDENTITY DILEMMAS [PDF]
CES Working Papers, 2014 This paper aims to present an important phenomenon of our world, namely the contradictory relationship between globalization and cultural identity. In this work identity is understood as a cultural practice therefore it cannot be analyzed without taking ...
Sebastian Andrei Labes
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Human Rights and Cultural Identity
Baltic Journal of Law & Politics, 2015 Universal human rights and particular cultural identities, which are relativistic by nature, seem to stand in conflict with each other. It is commonly suggested that the relativistic natures of cultural identities undermine universal human rights and ...
John-Stewart Gordon
doaj +1 more source
Analysis of Cultural Capital and Identity Formation in the Animated Movies "The Incredibles", "WALL-E", and "Ratatouille", Based on Pierre Bourdieu's Theory of Cultural Capital [PDF]
پیکرهIntroduction: This study examines and analyzes the representation of cultural capital and identity formation in the animations The Incredibles (2004), WALL-E (2008), and Ratatouille (2007).
Hamed Mirzaei +2 more
doaj +1 more source