Results 141 to 150 of about 1,535,014 (362)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Journal of Theoretical and Applied Electronic Commerce ResearchThe digital creative industry (DCI) has become an integral part of China’s strategic emerging industries. This paper, utilizing county-level data from Chinese digital creative enterprises in 2022, examines the locational factors influencing the spatial ...
Xiaoyi Luo, Ni Gao, Xiaoming Yuan
doaj +1 more source
Review of the Impact of Cultural Imperialism in the Context of Globalization to the Film Industry [PDF]
, 2021 Xinyi Chen, Siwen Shen
openalex +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
A personal narrative of a Muslim woman’s journey in the hospitality industry [PDF]
, 2010 This is a work-in-progress paper that offers an autobiographical exploration of the journey of a Muslim woman in the UK hospitality industry. As the researcher is the primary source of data, autoethnography is used as the method of data collection ...
Brown, Lorraine, Osman, Hanaa
core
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Urban Cultural Industry Management System and Public Economic Based on Improved Algorithm.
Comput Intell Neurosci, 2022 Xiong M.
europepmc +1 more source
Comparison of Industrial Dynamics of Food and Beverage Industry in Bulgaria, Romania and Greece [PDF]
Industry dynamic is a key indicator for sustainable industry growth. It depends on variety of factors on international and regional level. One of the important driving forces on international level is seen in the face of economic and political alliances.
Blagoev, Dimitar +2 more
core +1 more source