Results 161 to 170 of about 1,535,014 (362)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
CULTURAL CAPITAL, CULTURAL INDUSTRY AND INDUSTRIES CULTURE : CONCEPTUAL SEARCHES
Vestnik Tomskogo gosudarstvennogo universiteta. Kul'turologiya i iskusstvovedenie, 2020 openaire +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Liberating the modern Chinese football fan: a theoretical perspective [PDF]
The cultural and philosophical heritage of modernism underpinning general marketing management theory imparts profound implications for organisations operating in professional sport.
Cockayne, David, Wright, Len Tiu
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Popular Music-Style and Identity: International Association for the Study of Popular Music, Seventh International Conference on Popular Music. By Will Straw et al., editors. (Montreal: The Centre for Research on Canadian Cultural Industries and Associations, 1995. ISBN 0-7717-0459-3, pbk.) [PDF]
, 2001 John Bodner
openalex +1 more source
The role of the public service broadcasting in the european countries [PDF]
Broadcasting in particular has seen remarkable change from the days of single-channel public broadcasting systems. The audiovisual “explosion” is a cultural, social and economic phenomenon of global dimension.
Budacia Elisabeta Andreea
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source