Results 91 to 100 of about 169,941 (325)

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

60-YEAR REMOTE SENSING OBSERVATIONS REVEALED CROSS-CYCLE EVOLUTION OF THE BRUNT ICE SHELF IN THE CONTEXT OF GLOBAL WARMING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The Antarctic Ice Sheet (AIS) holds the potential to raise global sea levels by a staggering 57 m. Ice shelves, extensions of these ice sheets into the ocean, play a crucial role in stabilizing the upstream ice sheet.
Y. Cheng, Y. Cheng, J. Xue, J. Xue, H. Yu, G. Hai, G. Hai   +6 more
doaj   +1 more source

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

Terminologia de informática em língua portuguesa: uma análise lingüística e terminológica

Ciência da Informação, 1989
A terminologia especializada na área de Informática, embora recente, tem-se revelado bastante produtiva nos países que desenvolveram esta tecnologia. A chamada transferência da tecnologia vem sendo acompanhada, concomitantemente, por uma "transferência ...
Ligia Maria Café de Miranda
doaj  

The Learning Style Decoder: FSLSM-Guided Behavior Mapping Meets Deep Neural Prediction in LMS Settings

Computers
Personalized learning environments increasingly rely on learner modeling techniques that integrate both explicit and implicit data sources. This study introduces a hybrid profiling methodology that combines psychometric data from an extended Felder ...
Athanasios Angeioplastis, John Aliprantis, Markos Konstantakis, Dimitrios Varsamis, Alkiviadis Tsimpiris   +4 more
doaj   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Predicting Student Performance and Enhancing Learning Outcomes: A Data-Driven Approach Using Educational Data Mining Techniques

Computers
This study investigates the use of educational data mining (EDM) techniques to predict student performance and enhance learning outcomes in higher education.
Athanasios Angeioplastis, John Aliprantis, Markos Konstantakis, Alkiviadis Tsimpiris   +3 more
doaj   +1 more source

Participatory, Visible and Sustainable. Designing a Community Website for a Minority Group [PDF]

, 2012
This paper tackles three aspects of community-based technological initiatives aimed to support minority groups’ public expression and communication: participation, visibility and sustainability.
Agosti, Matteo, Paolini, Paolo, Sabiescu, Amalia E.   +2 more
core  

Ethical issues of electronic patient data and informatics in clinical trial settings [PDF]

, 2006
The field of cancer bio-informatics unites the disciplines of scientific and clinical research withclinical practice and the treatment of individual patients.
Ingram, D, Kalra, D
core   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source