Results 101 to 110 of about 1,986,126 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

From Silos to Synergy: Redefining Collaboration in the Performing Arts and Museum Sectors

open access: yesArts
The arts sector—museums, theaters, and orchestras—in the United States and Europe faces increasing financial and operational challenges, from declining attendance to reduced public and private funding.
Christos A. Makridis
doaj   +1 more source

THE APPLICABILITY OF STRATEGIC ANALYSIS METHODS FOR COMPETITION ENVIRONMENT IN THE DIAGNOSIS OF CULTURAL ORGANIZATION IN REGIONAL CONTEXT [PDF]

open access: yes
Culture has various dimensions, from instrument of communication and promotion of national values and expression of the national spirit to ways of spending free time.
Razvan-Andrei CORBOS
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

THE SOCIAL - ECONOMIC AND CULTURAL CHARACTERISTICS OF THE ROMANIAN - BELGIAN RELATIONSHIPS [PDF]

open access: yesStrategii Manageriale, 2014
Belgium may be, for some of the Romanians, an experience outside the home country borders. The adaptation is done in time, for each one, it matters very much how you got in the destination country.
Cristina-Maria, PESCARU
doaj  

Diversity in the Heartland of America: The Impact on Human Development in Indiana [PDF]

open access: yes, 2018
This article is the third in a series of studies measuring the impact of cultural diversity on human development. We disaggregate cultural diversity into three components: ethnicity, language, and religion.
Boothby, Lisa   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Building a Continent: MoMA’s Latin American Architecture Since 1945 Exhibition

open access: yesARQ
Latin American Architecture Since 1945 sought to highlight the achievements of modern architecture in the region, but, in retrospect, it resulted in a partial and idealized view.
Patricio del Real
doaj   +1 more source

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