Results 121 to 130 of about 1,986,126 (300)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Immigrant cultural entrepreneurs in São Paulo in the 1950's

Tempo Social
This paper discusses the relationship between immigration, industry, diversification of the elites and the creation of cultural institutions in São Paulo in the 195's, a time of intense city dynamics when it was acquiring the definite shapes of a ...
Maria Arminda do Nascimento Arruda, Deborah Neale   +1 more
doaj  

Cultivating Community: The role of the Winooski school system in creating positive relationships between city institutions and the refugee population [PDF]

, 2017
Schools serve as key institutions for absorbing newcomers into American society, as they provide resources, programming, and access points into a community for immigrant children and their families. In Winooski, Vermont, the public school building serves
Hurwitz, Rachel M
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Book Review of Ronald B. Hoch and David P. Smith’s Old School, New Clothes: The Cultural Blindness of Christian Education

, 2012
Excerpt: In Old Schoo; New Clothes, Hoch and Smith accuse Christian schools of being blind to the forces and forms of modernity, in fact not only blind, but founded on the very same principles as public schools.
Badley, Ken
core  

Changing Practice in a National Legal Deposit Library [PDF]

, 2006
This two-part essay considers how digital culture has influenced ideas about permanence and looks at the change in collecting practice in a legal deposit library.
Mason, Ingrid
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Museum Critique in Contemporary Artistic Practices: Collecting, Captioning, Displaying, Exhibiting

Miranda: Revue Pluridisciplinaire du Monde Anglophone
This article presents a case study of the work of a contemporary artist, Ed Atkins, whose practice is based on the collection and arrangement of objects and the production of critical texts about them.
Adrian Fix
doaj   +1 more source

Public institutions of “high” culture [PDF]

, 2015
This chapter focuses on institutions that distribute “high” culture via public or quasi-public mechanisms. High culture includes (Western) fine arts, such as classical and contemporary visual arts, opera, classical music, and ballet. The chapter covers art museums, symphony orchestras, and opera, drama, and dance companies, organizations comprising ...
openaire   +1 more source