Results 71 to 80 of about 1,986,126 (300)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Научный диалог, 2018 The relevance of the topic is due to modern interdisciplinary research in the field of historical anthropology and social history, covering the period of the USSR.
A. V. Lipatov +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Australian best practice guide to collecting cultural material [PDF]
INTRODUCTION Australia’s public collecting institutions enrich public life by displaying, interpreting, making accessible and preserving the world’s shared cultural, scientific and historic heritage.
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Valuing knowledge transfer : a new approach to assessing the broader impact of higher education institutions [PDF]
, 2009 There is considerable policy interest in exploring the overall value of higher education to society and in how higher education can support wider economic growth and development through 'knowledge transfer' from higher education institutions.
Kelly, Ursula +3 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
De la trinxera al màster: un nou espai formatiu per a la gestió de la cultura
Digithum, 2006 La posada en marxa del nou espai europeu d'ensenyament superior implica nous reptes a l'hora d'abordar la formació dels professionals de la gestió cultural i la gestió del patrimoni. No es tracta només d'elaborar uns plans formatius més o menys complets,
Laura Solanilla
doaj +1 more source
The lost value for users of cultural institutions during the COVID-19 pandemic: a life satisfaction approach. [PDF]
Int Rev Econ, 2023 Baldin A, Bille T.
europepmc +1 more source