Results 81 to 90 of about 158,318 (267)
TarbawiThis study examines how Qur’anic education can be strengthened by integrating local cultural values into formal schooling. The purpose of this research is to develop an empirical framework for integrating Qur’anic teachings with indigenous cultural ...
Syafrul Nalus +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Critical Perspectives in English Language Teaching, What is Coming?
HOWThis reflective article examines the emerging tendencies in critical perspectives within English Language Teaching (ELT). The article begins by providing a brief historical overview of ELT's critical pedagogies and discussing its perspectives in the ...
Angela Patricia Velásquez Hoyos +1 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Inclusive Leadership in Higher Education: Strategies for Dealing with Student Diversity
ManagereThis research aims to explore inclusive leadership strategies in managing student diversity in multicultural universities in Indonesia. Using a qualitative approach based on intrinsic case studies, data were obtained through in-depth interviews, policy ...
Cliford Ratulangi, Raymond Piring
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Tolerance Tourism: A Historical Perspective on Cultural Integration in Glodok Chinatown Jakarta
HumanioraThe research examines the multifaceted history of tolerance tourism in Glodok Chinatown, Jakarta, Indonesia, with a focus on the Peranakan Chinese community and its unique cultural heritage.
Zsarin Astria Puji Insani +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Revista Iberoamericana de Estudios de DesarrolloThis study examines the determinants of job quality among Venezuelan migrants in Peru, a country that has received one of the largest migration flows in the region in recent years.
Héctor Javier Bendezú-Jiménez +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source