Results 201 to 210 of about 66,987 (261)

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

A scoping review and thematic analysis of the landscape of spiritual health and spirituality in Canada. [PDF]

open access: yesPLoS One
Boutros HM   +7 more
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

A scoping review of mental health counseling practices, challenges, and prospects in Ethiopia. [PDF]

open access: yesDiscov Ment Health
Woldemichael A   +4 more
europepmc   +1 more source

Bridging landscape and perceived restorativeness: an empirical study of greenways along the Grand Canal, Hangzhou. [PDF]

open access: yesFront Psychol
Wang Y   +10 more
europepmc   +1 more source

Abstract Cultural Landscapes

Journal of Cultural Geography, 1987
(1987). Abstract Cultural Landscapes. Journal of Cultural Geography: Vol. 8, No. 1, pp. 67-80.
openaire   +1 more source

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