Results 61 to 70 of about 4,657,899 (291)

Open Space and Urban Sprawl: The Effects of Zoning and Forest Conservation Regulations in Maryland [PDF]

Rapid urbanization enhances the desirability of policies for preserving open space but policies intended to preserve open space may extend the urban boundary and create leapfrog development.
Lichtenberg, Erik
core  

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Landscape architecture as means of forming national identity in public spaces in buffer zones of Ukrainian cultural heritage objects

Current problems of architecture and urban planning, 2023
У статті представлено результати авторського дослідження щодо формування національної ідентичності в громадських просторах засобами ландшафтної архітектури; розглянуто поняття «національної ідентичності» в архітектурі та містобудуванні; наведено характеристику громадських просторів на основі соціополітичного фактора (тоталітарні та демократичні).
openaire   +3 more sources

Lot Size, Zoning, and Household Preferences: Impediments to Smart Growth? [PDF]

The paper explores a number of issues related to lot size and urban density. First, trends in single-family residential lot size over the past 35 years are examined in eight counties in the state of Maryland.
Kopits, Elizabeth, Miles, Daniel, McConnell, Virginia   +2 more
core  

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Spatial Expansion, Planning, and Their Influences on the Urban Landscape of Christian Churches in Canton (1582–1732 and 1844–1911)

Religions
Canton (present-day Guangzhou, China) has a long history as a trading port and serves as a window for studying the history of Sino-Western cultural exchanges.
Yonggu Li
doaj   +1 more source

Zoning, TDRs, and the Density of Development [PDF]

Many communities on the urban fringe are implementing a range of policies to preserve farmland and open space, cluster residential development, and guide development to areas with existing infrastructure.
Walls, Margaret, Kopits, Elizabeth, McConnell, Virginia   +2 more
core  

Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis

Advanced Science, EarlyView.
Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun, Zhensheng Yue, Zhiqiang Fang, Hao Xu, Wei Du, Yuwei Ling, Jingjing Liu, Ping Song, Fei He, Juanli Duan, Lin Wang   +10 more
wiley   +1 more source

How does road networks impact cultivated land multifunctionality? The role of land fragmentation: evidence from Hubei Province, China

Frontiers in Sustainable Food Systems
Understanding the influence mechanisms of road networks on cultivated land multifunctionality (CLM) is critical for optimizing territorial spatial patterns and achieving sustainable cultivated land resource management.
Fan Liu, Weiyan Hu, Min Min, Tian Liu, Shixiang Li, Qi Rong   +5 more
doaj   +1 more source