Results 61 to 70 of about 1,856 (250)

Soil, vine and other quality cultures: “terroir” and “zonazione” concepts introduction and practice

open access: yesItalian Journal of Agronomy, 2008
The research of the cultural vocation is one of the most effective means for quality and typicality protection of the productions and, at the same time, to limit soil degradation. In particular, the study of “terroir”, i.e.
Edoardo A.C. Costantini   +1 more
doaj   +1 more source

Waimea's Heritage Landscape: Using GIS to Communicate Change and Significance of a Cultural Landscape in South Kohala, Hawaiʻi

open access: yes, 2018
Hawaiʻi County’s Land Use Pattern Allocation Guideline map (LUPAG) show an increase in lands being allocated for urban development in the South Kohala District of Hawaiʻi Island.
Plunkett Jr., Samuel W.L.
core  

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng   +10 more
wiley   +1 more source

A general plan for Moisionpelto and Pappilanpelto local recreation area in Lohja; An invigorating cultural landscape park [PDF]

open access: yes, 2022
Kulttuurimaisemien ja luonnon monimuotoisuuden vaaliminen ovat ajankohtaisia aiheita, niin maailmanlaajuisesti kuin kotimaassamme. Maanviljely ja peltojen käyttö on ollut ajankohtainen aihe kautta aikojen ja on sitä tälläkin hetkellä. Peltojen säilyminen
Pääkkönen, Linda
core  

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Geotourism: A Landscape Conservation Approach in Țara Hațegului, Romania

open access: yesLand
This study focuses on Țara Hațegului, a region with significant geological, ecological, and cultural resources, and examines how geosites can inform development strategies that promote geotourism while supporting landscape conservation.
Daniela-Ioana Guju   +2 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Deep Learning-Driven Garden Design: Integrating AI Into the Creative Process

open access: yesIEEE Access
The integration of artificial intelligence into landscape architecture has opened new frontiers for computational design, enabling the generation of garden and outdoor spatial layouts that blend ecological logic with aesthetic innovation.
Han Yang, Dong Zheng, Lianyu Wang
doaj   +1 more source

Experiencias de análisis territorial y zonificación para la integración del desarrollo, el patrimonio y el paisaje en la ordenación del territorio [PDF]

open access: yesCiudades, 2012
We present a series of experiences of territorial analysis for zoning in the context of regional planning. They are based on a methodology that allows the integration of all territorial values and provides an adequate basis for the development of ...
Juan Carlos García Codron   +2 more
doaj  

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