Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Classification of Traditional Handmade Papers from China, Japan, and Korea Using NIR Hyperspectral Imaging. [PDF]
Lee YJ +5 more
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Transforming urban parks into comprehensive-health- promoting spaces. [PDF]
Gan D, Wang T.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The impact of cultural leisure activities participation on older adults' subjective well-being: an empirical study in China. [PDF]
Ji R, Sheng Y, Zheng C, Chen W.
europepmc +1 more source
Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen. [PDF]
Gabriel D +4 more
europepmc +1 more source
The construction of placeness in traditional opera from the perspective of structuration theory: A case study of Huangmei Opera in Anqing, China. [PDF]
Zhu F, Su Q, Xu J, Zhu L.
europepmc +1 more source
Internet use, cultural consumption, and subjective well-being: exploring the mediating role in rural China. [PDF]
Wu P, Zhang M, Chang Q, Ying J.
europepmc +1 more source

